USP7 anticorps
Aperçu rapide pour USP7 anticorps (ABIN7120532)
Antigène
Voir toutes USP7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- USP7 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- ubiquitin specific peptidase 7
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
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Autre désignation
- USP7
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Sujet
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 7|Deubiquitinating enzyme 7|Herpesvirus-associated ubiquitin-specific protease|Ubiquitin thioesterase 7|Ubiquitin-specific-processing protease 7|USP7|HAUSP
Background: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
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Poids moléculaire
- 130 kDa
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ID gène
- 7874
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UniProt
- Q93009
Antigène
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